Series 1: Personal Papers, 1885-1977, is arranged by creator into four subseries. The D. P. Wine sermon daybook is a bound ledger containing dates and types of sermons or ceremonies performed by Wine. Included are weekly church sermons with Bible verses referenced, funerals preached at by Wine, baptisms performed, and marriages in which Wine acted as the officiant. Loose handwritten obituaries were removed and foldered separately. Financial documents related to D. P. Wine's estate are included.

The materials related to J. D. Wine primarily document his involvement in community organizations – the Lee District Sunday School Association, the Anti-Saloon League of Shenandoah County, and his local church council. His financial activities are documented in a series of ledgers and cashbooks.

J. C. Wine's papers provide a more holistic view of his life and include materials relating to his early schooling, his career with the Union Life Insurance Company (ULICO), his involvement in church activities, and diaries written during the latter part of his life. The two diaries, 1970-1977, by J. C. Wine provide detailed daily accounts of local, national, and international happenings. J. C. documented notable news of the day (Richard Nixon's resignation, Apollo 14 mission), local births and deaths including the New Year babies born at local hospitals, weather reports, and personal and community updates. There are often numerous entries per day and the entries appear to reflect news likely reported in the local newspaper.

Two miscellaneous items, an unidentified time book and a ledger presumably belonging to Samuel Good, are grouped together.

Series 2: Photographs, 1897-1986, is comprised of loose photographs and bound photo albums primarily of Wine family members. The photographs, many of them identified, document Black Water Falls, Fort McHenry (Baltimore, Maryland), Fort Belvoir (Fairfax County, Virginia), Camp Bethel (Fincastle, Virginia), and scenes of daily life. Community members and friends are depicted (including John C. Myers, 1876-1962, of Broadway), as are family pets and animals. Photographs of Naomi Zirkle Wine's father's 90th birthday are included along with a register of the guests. Miscellaneous photographs include scenes of the National Mall in Washington, DC, the John F. Kennedy funeral procession, and persons who are likely community members or friends, but are otherwise unidentified. Additionally, a signed headshot of country music singer Roy Acuff and a signed facsimile of country music singers Lee and Juanita Moore and their son Roger Lee are included.

Series 3: Scrapbooks and Ephemera, 1903-1998, includes a large selection of blank postcards, both bound in scrapbooks and loose. The scrapbooks also contain greeting cards, with one documenting the birth of J. D. and Naomi Wine's daughter, Mary Sue Wine, and a second documenting J. C. Wine's various medical procedures and hospital stays during 1967-1972. One scrapbook is comprised of menus, newspaper clippings, programs for local music and theatre performances (New Market Theatre), beauty pageants, local church events, high school commencements (New Market, Triplett, Timberville), and related ephemera. Loose postcards depict local scenes as well as national landmarks and scenes of Washington, DC and New York City. Pamphlets and brochures related to J. C. Wine's involvement with the Masonic Lodge and Shriners International are included.

Series 4: Genealogical Materials, 1892-2001, document the Wine family and the related Myers, Zirkle, and Huffman families. The only correspondence in the collection is filed within this series as it relates strictly to Myers family history and their connection to the Wines. The letters are chiefly from Jennie R. Driver to J. D. Wine. J. D. Wine was a great-great grandson of Barbara Wine Myers and Samuel Myers.