Prince George County was formed from Charles City County by a statute adopted on 28 August 1702 to take effect on 23 April 1703. The county was named for Prince George of Denmark, husband of Queen Anne of England.

Most court records were destroyed in 1782 by British troops during the Revolutionary War and again in 1864 by Union troops during the Civil War. A few volumes that record deeds, court orders, and wills exist.

The separate office of coroner appeared in Virginia about 1660. The judicial duty of the office is to hold inquisitions in cases when persons meet sudden, violent, unnatural or suspicious death, or death without medical attendance. The coroner would summon a jury to assist him in determining cause of death. Prior to November 1877, the jurors numbered twelve. Between November 1877 and March 1926, the jurors numbered six. The jury viewed the body of the deceased and heard the testimony of witnesses. The coroner was required to write down witness testimony. After seeing and hearing the evidence, the jury delivered in writing to the coroner their conclusion concerning cause of death referred to as the inquisition. After March 1926, only the coroner determined cause of death. He could require physicians to assist him with determing cause of death. If a criminal act was determined to be the cause of death, the coroner was to deliver the guilty person to the sheriff and the coroners' inquests would be used as evidence in the criminal trial.