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This is a history, "Westward Down the Ohio," relating highlights of Ohio River history, ca.1750-1880, in West Virginia. Subjects include early exploration, settlement, and transportation, especially the steamboat era. Mention is often made of events occurring in Parkersburg and its vicinity as being typical examples of the history of the Ohio Valley.

Correspondence, business and legal papers, surveys, account books, and a diary of a Burning Springs surveyor, oil developer, rural entrepreneur, horticulturalist, and captain of the Little Kanawha River steamer GENERAL JACKSON. Collection includes a brief journal of a trip from Des Moines, Iowa, to the Forks of the Platte in 1860; papers of Clarke's venture in quartz mining and milling in the Colorado Territory, 1861-1863; surveys of the Burning Springs oil region; letters from James C. Clarke, president of the Wirt Oil and Mining Company of which Clarke was superintendent; papers on the National Grange, the West Virginia Grange (Patrons of Husbandry), cooperatives, and the Ohio, Pennsylvania, and West Virginia Wool Growers Association; a diary of farming operations at Burning Springs; letters from Clarke's brother, James C., while a member of the Pennsylvania senate, 1875-1880; letterheads from Little Kanawha and Ohio Valley mercantile firms and steamboat companies; and family letters. Other subjects covered include: the Allegheny Valley Railroad; early history of Bethalto, Illinois; the speculative spirit and western expansion, 1860; freighting on the Great Plains during the Civil War; construction of the Chicago, Rock Island, and Pacific Railroad near Council Bluffs in 1868; and the effect of the German crisis of 1866 on American oil prices.

M.K. Lowther (1869-1947) was a journalist and one of the first women newspaper editors in West Virginia. She was the author of the HISTORY OF RITCHIE COUNTY; BLENNERHASSETT ISLAND IN ROMANCE AND TRAGEDY; FRIENDSHIP HILL, HOME OF ALBERT GALLATIN; MARSHALL HALL AND OTHER POTOMAC POINTS IN STORY AND PICTURE; and MT. VERNON: ITS CHILDREN, ITS ROMANCES, ITS ALLIED FAMILIES AND MANSIONS. There are complete and incomplete typescripts, rough drafts, revisions, photographs and plates of her books. Also there are typescripts of news articles on Washington, D.C., the Potomac Valley, and Wood County. There are genealogical notebooks and correspondence and also correspondence to publishers concerning business arrangements. Families mentioned are: Ball, Barber, Bee, Brake, Broadwater, Burns, Chenoweth, Clayton, Collins, Corbitt, Cox, Cunningham, Davis, Day, Dougherty, Drake, Fittro, Fitzrandolph, Goff, Hall, Hardman, Harris, Haymond, Henderson, Hoff, Hughes, Ireland, Jackson, Johnson, Kapkin, Kendall, Kercheval, Kuykendall, Leep, Leg(g)ett, Lemon, Lowther, McDougal, McGinnis, McGregor, McNeill, Marsh, Maxwell, Meredith, Minear, Modesitt, Morgan, Morrison, Murphy, Null, Nutter, O'Maley, Piatt, Pierpont, Pribble, Prunty, Ralston, Reger, Riddel, Riddle, Scott, Sharp, Shinn, Sleeth, Smith, Stump, Taylor, Waldo, Web(b), Willard, Willis, Wilson, and Zinn.

Papers relating to the early development of Marietta and the Ohio Valley include the journal, 1784-1790, and correspondence, 1776-1824 (3 vols.), of a Revolutionary War officer and organizer of the Ohio Company, General Rufus Putnam; papers of Samuel Prescott Hildreth entitled: "Early Events in the Valley of Ohio, 1787 to 1847" (2 vols.); letter from Nathan Goodale to Rufus Putnam, 15 March 1788; journal of Joseph Buell, 1785-1789; and a journal of John Mathews, 1786 (holograph copy).

Newspaper clippings, picture-books, postcard albums, and government reports relating to floods along the Ohio River Valley especially at Pittsburgh, Wheeling, and Parkersburg.