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This addition to the papers of Senator Harry F. Byrd, Jr., of Winchester, Virginia, contains ca. 3,100 items, (10 Hollinger boxes, one oversize folder, and 83 bound volumes, ca. 19 linear shelf feet) ca. 1925-1989, consisting chiefly of bound scrapbooks, bound copies of speeches and press releases, and Congressional Record speeches and inserts, documenting his life and career during his service in the U.S. Senate, 1965-1982; news clippings; a folder of material concerning the Winchester Junior Board of Trade; a report on the "Study of the Organization of the State Government of Virginia" (1947 Dec 29); and personal and professional correspondence during his eighteen years in the Virginia Senate.

Drawings of varying size, political cartoons, sculpture, books, framed items, scrapbooks, sketchbooks, slides, video tapes, and news clippings.

The University Archives Audiovisual Collection is an artificial collection of various audio and visual formats documenting the College of William and Mary campus, events, people, etc. The collection contains analog, magnetic, and digital media and while not comprehensive, it does include material from a variety of time periods and types of events including commencements, Charter Day, building dedications, lecture series, Raft Debates, visiting scholars and distinguished guests, athletic events, and much more. Researchers are encouraged to verify with staff the format of individual items and availability for immediate use. Many items in the collection will require preservation reformatting before they can be used.

This collection consists of the organizational archives and research papers presented by members of Lexington, Virginia's Fortnightly Club, a men's club organized with the purpose of discussion of current topics and social engagement. The club was founded in 1900 after similar clubs in Newburyport, Massachusetts (also called the "Fortnightly Club") and the "Conversation Club" of Louisville, Kentucky.

This collection contains the entirety of General Samuel Vaughan Wilson's personal and professional papers, as donated to Hampden-Sydney College by his widow in 2019. Topics include the Vietnam and Second World Wars, the development of the United States of America's intelligence and counter-intelligence communities, military strategy, and Wilson's role as president of Hampden-Sydney College from 1992 until 2000.

Inventoried collection of correspondence, poems, essays, mementos, and personal effects of Elizabeth Carrington Eggleston, daughter of former Hampden-Sydney College President Joseph DuPuy Eggleston, including numerous "jotting books" or commonplace books that Eggleston kept throughout her life.

The Edward Watson Hook papers reflect his wide-ranging professional activities related to heading the Department of Internal Medicine, participating in the larger Health System/University processes, and pursuing his own research and external activities. The documents detail Hook's direct personal participation in professional organizations and also show the wide range of details he coordinated in running the department of internal medicine. A noteworthy aspect of the collection includes an unpublished History of the Department of Medicine written by Byrd Leavell. Hook read and critiqued the manuscript, but Leavell died before completing the book. Also, Hook conducted a series of interviews with Thomas H. Hunter which complement with the Thomas H. Hunter papers, MS-4, Claude Moore Health Sciences Library.

The John A. Owen, Jr. Papers consist of 15 boxes of archival material including letters, research notes, and documentation, and other items which reflect his professional activities from 1951-1995. The materials especially focus on diabetes, obesity, and endocrinology research; the relationship between pharmaceutical companies and physicians; federal regulations on prescription writing; and pharmacist-physician interaction. This collection is of special interest to scholars interested in the University of Virginia's clinical investigation during the 1960s-70s on diabetes and endocrinology; the relationship between pharmaceutical companies (and other organizations sponsoring basic research) and physicians; the effect of and response to federal legislation of the early 1970s which regulated prescription writing; the role of the pharmacist and their relationship to the physician; the interaction of the University of Virginia's department of medicine with the hospital's lab/pathology department; and the use of free samples from drug companies.