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The Hoge Family was one of the earliest settlers of the New River area of southwest Virginia. William Edward Hoge and his family resided in Point Pleasant, Bland County Virginia, where William Hoge began his medicinal practice in 1855. Hoge was married to Jane L. Meek, and they had three sons and one daughter. The William E. Hoge Family Papers consist of 164 letters and 65 deeds, along with financial papers, postcards, and extensive genealogical research. The letters detail the lives of the Hoge family, specifically the children, from the 1830s through the 1880s. Several of the letters in the collection are written by Ollie Hoge, spanning from the time when she was a young girl enrolled in the Wytheville Female College to her later days as a wife and mother living in Richmond.

One hundred and fifty-six documents, dating from 1784 to 1837, mounted and bound in a single volume. The collection contains business papers of William Ewin, of St. George, Tucker County, West Virginia, 1835 to 1850, subsequently a surveyor of prominence in West Virginia, and a member of the West Virginia State Senate (1879-1882). Approximately one third of the collection consists of patents, surveys, and other papers pertaining to wild lands in Randolph County, (West) Virginia, of which William Ewin owned a large acreage.

Several thousand pieces mounted in bound volumes. Ewin, whose home was in St. George, Tucker County, was a land speculator who owned and developed large holdings in Barbour, Preston, Randolph, and Tucker Counties. He was a surveyor and surveying instrument maker in Baltimore Maryland, from about 1835 to 1850 and was a member of the West Virginia State Senate, 1879-1881.

William F. Randolph (1800-61) and some of his children and father's papers. Randolph's father, Johnathan, a Harrison Co. justice of the peace, and his predecessors were prominent farmers near Salem. Randolph, who owned a farm south of Salem on Greenbrier Run, was a surveyor, and later a justice of the peace of early Doddridge Co. Some of the papers concern the estate of Johnathan Randolph and the legal conflict between Isaac Randolph, his son, and other heirs. There are estate papers for William F. Randolph and also for his son, Ezra Randolph. Also included are court settlements in which Randolph was involved (mainly Samuel Bond and Jane Van Horn) and his business papers of the Salem-Harrisville turnpike. There are land, tax, militia, store, church, school, debt and news subscription receipts of William Randolph and his children. Also there are manuscripts developed on the basis of this collection by the donor about the Randolph family and early Doddridge County.

Correspondence and miscellaneous papers of: a Monroe County, West Virginia, farmer and politician; his wife, Harriette Boswell Alexander; their daughters, Isabel and Alice Beulah; Alice's husband, Frank Hereford, U.S. senator from West Virginia; and his daughter, Katherine Hereford Stoddard. There is one folder of business papers, 1820-1841, of Thomas Edgar; a few letters from Caperton's son, John, while a cadet at the Camp of Instruction, Richmond, 1861; a folder of letters concerning Isabel's trips through the American West, the British Isles, and Europe; and a folder on family genealogy. Subjects include mid-nineteenth century life in Union, Monroe County; the excitement in Virginia following John Brown's raid; Washington, D.C., and the slavery controversy, 1860; the secession crisis in Virginia; impressment of material in Monroe County by Union troops; the effect of the war on the social and economic life of Richmond; work of the Ladies Relief Hospital in Lynchburg; and the aftermath of war in Virginia.