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Correspondence and documents pertaining to the West Virginia Asylum for the Incurables, now Huntington State Hospital, mainly concerning the location of a suitable site by the office of the secretary of state. Correspondents include John W. Davis and W.A. MacCorkle.

Bills, receipts, and letters of Kincaid of Greenbrier County, West Virginia, mainly concerning his attempts to obtain a position at the Richmond, Virginia insane asylum as a medical student and his various contacts with Greenbrier County as a school teacher. Also there is a Renick family history.

A scrapbook and clippings, advertisements, letters, manuscripts of speeches, and notes on medical practice, compiled by Dr. John Frissell (1810-1882), a physician at the Wheeling Hospital and medical superintendent of military prisoners and soldiers in Wheeling during the Civil War. The scrapbook is a folio volume, Register of the Sick and Wounded, U.S.A. General Hospital. There is also information on the Medical Society of the City of Wheeling, the West Virginia Medical Society, medical conventions in West Virginia, and Wheeling local history.

County court records concerning court cases and proceedings, as well as some public records, primarily tax, birth, death, and marriage records. There is also a large collection of private account books from various local businesses.

Correspondence of William A. Harrison, a Clarksburg lawyer, assistant federal district attorney, member of the Virginia Assembly, and judge of the Supreme Court of Appeals of West Virginia; most letters are from members of the family to Mrs. Anna Robertson Harrison. Subjects include construction of the Chesapeake and Ohio Canal; Civil War loyalty Oaths, Camp Chase land purchases, and road building. There are also grade school attendance certificates and notes concerning the Lunatic Asylum West of the Allegheny Mountains and Weston State Hospital.

Original appraisement and account book pertaining to the estate of John S. Camden, 1862-1881. There are two ledgers of T.B. Camden, a physician, covering his medical practice in sixteen counties, listing private accounts, cost of medical care, insurance claims, and statements of Camden's income, 1865-1907. There is a scrapbook of clippings, numerous broadsides, and correspondence on professional and political activities of Camden including letters from friends regarding his dismissal as superintendent of the state hospital for the insane at Weston. The microfilm includes entries from the diary of Thomas S. Feamster, a Confederate soldier, noting troop movements in Greenbrier County, 1861, 1864-1865, and entries from the commonplace book of Theodore Woodridge.

Account ledger of Weston State Hospital (formerly the Lunatic Asylum at Weston) for the mentally ill. Over 360 pages, it includes transactions listed chronologically by month for period January 1866 to March 1868, and by day for 1873-1887. Many of the entries document construction expenses. Although patients were first admitted in 1864, construction of the facility continued until 1881.

Correspondence and miscellaneous papers of: a Monroe County, West Virginia, farmer and politician; his wife, Harriette Boswell Alexander; their daughters, Isabel and Alice Beulah; Alice's husband, Frank Hereford, U.S. senator from West Virginia; and his daughter, Katherine Hereford Stoddard. There is one folder of business papers, 1820-1841, of Thomas Edgar; a few letters from Caperton's son, John, while a cadet at the Camp of Instruction, Richmond, 1861; a folder of letters concerning Isabel's trips through the American West, the British Isles, and Europe; and a folder on family genealogy. Subjects include mid-nineteenth century life in Union, Monroe County; the excitement in Virginia following John Brown's raid; Washington, D.C., and the slavery controversy, 1860; the secession crisis in Virginia; impressment of material in Monroe County by Union troops; the effect of the war on the social and economic life of Richmond; work of the Ladies Relief Hospital in Lynchburg; and the aftermath of war in Virginia.