- Edward Meeks "Pope" Gregory papers, 1967/199535
- Eleanor P. Sheppard papers, 1924/1978460
- Elisabeth Scott Bocock papers, 1928/1985160
- Elizabeth Cramer LGBT activism collection, 1991/201351
- Elizabeth Magie papers, 1942/19437
- Elizabeth Smith collection of Virginia ERA Ratification Council records, 1970/2002134
- Emily Dickinson letter to Mrs. Henry Hills, 18791
- Emma Gray Trigg papers, 1920/1971108
- Encampment for Citizenship collection, 1939/2009176
- Equality Virginia records, 1972/2008106
- Ernest M. Gunzburg papers, 1915/198937
- Etuy Elizabeth Hall papers, 1927/198619
- Eugene V. White papers, 19251
- Evelyn Crary Bacon papers, 1936/1997219
- Fan District Association records, 1964/201238