- S. Eliot Breneiser Papers, 1965/197597
- Samuel J. Major Collection, 1861/186511
- Samuel Leyens Switzer Papers, 1910/1985203
- Schola Cantorum Records, 1995/201672
- School of General Studies Records, 1950/1989180
- School of Graduate Studies Records, 1970/197793
- Scott R. Sechrist Papers, 1970/19742
- Shipbuilding Ledger (Norfolk, Va.), 1796/186011
- Stanley Clay Walker Papers, 1950/20001,014
- Steven A. Yetiv Papers, 1983/201218
- Strauss Family Papers, 1839/193587
- Student Organizations Collection, 1941/2025134
- Student Wives Club Records, 1961/197721
- Susan Kent Papers, 1975/200346