- S. Eliot Breneiser Papers, 1965/19752
- S. F. (Bill) Royall, Jr. papers, 1883/19791
- Samuel A. Mann Papers, 1863, 191482
- Samuel H. McNutt Papers, 1861-1864.7
- Samuel Herrick Papers, 1930/197426
- Sara Teasdale Collection
1888-19349
- Scrapbook of Governor Lawrence Douglas Wilder, 1990-19921
- Scrapbooks, 1914/201117
- Secretary of Administration, Records, 1998-200121
- Secretary of Finance, 1998-20011
- Secretary of Natural Resources Correspondance and Subject Files, 1990-19982
- Secrets of the Sequence records, 2000/20074
- Selma Plantation Real Estate Records3
- Sena Sekulić-Gvozdanović Architectural Collection, 1963/20023
- Senator Charles Waddell Scrapbooks, 1967-20013