- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969207
- Eleanore Pettersen Architectural Collection, 1915/2003, bulk 1950/200061
- Charles Goodsell Collection, 1982/200157
- Leonard J. Currie Papers, 1920/200147
- Blake W. Corson, Jr., Papers, 1861/1984, bulk 1934/197936
- Records of the Virginia Tech University Libraries, 1925/200632
- Records of the Office of the Vice President for Administration, Stuart K. Cassell, 1945/197531
- Records of the Virginia Cooperative Extension, 1862/199726
- Roy Jay Holden Papers, 1904/194526
- Black Women at Virginia Tech Oral History Project Records, 1967/2000, bulk 1994/200015
- Records of the Virginia Tech Board of Visitors, 1873/200913
- Charles Willis Cassell Family Papers, 1883/19508
- Audrey Emmons Architectural Collection, 1974/19975
- Bailey-Law Collection, 1825/19714
- Southside Garden Club Records, 1914/20093