- Admiral Thomas J. Lopez Papers, 1973/201417
- Adolphus DeBussey, Soldier, Civil War Letters, 1861/1998, bulk 1861/187194
- Aileen Shafer, Collector, Material regarding African-Americans, 1829/188420
- Albert M. Reese (1872-1965) Papers, 1907/195416
- Albert Moore Reese, Zoology Professor, Miscellaneous Items, 1900/197047
- Alexander Mahood, Architect, Drawings for West Virginia University Building Projects, 1955/19791
- Allen Family Papers, 1766/19331
- Alvena V. Seckar, Author and Artist, Writings, Photographs, Scrapbooks, and Other Material, 1927/20056
- Amalgamated Association of Street and Electric Railway Employees of America, Division 103, Archives, 1899/195862
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20112
- Ann Magnuson, Performance Artist, Papers, 1973/20245
- Anna Schein, Collector, Feedsack Textile Bag Collection, 1925/19653
- Appalachian Prints Collection, 1839/2010, bulk 1859/1909254
- Artemis Sisters Collective Records, 1980/2024, bulk 1980/199418
- Arthur Jacknowitz Faculty Papers, 1954/20194