- Carl B. Allen Papers Regarding Early Aviation, 1918/19713
- Carl George Krieger Papers, 1930/196814
- Charles H. Ambler (1876-1957) Papers, 1913/19573
- Charles Peters, Editor and Author, Papers, 1975/201652
- Charles Vandersee papers, 1974/19962
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/20184
- Christopher Kolawoski newspaper collection, 1946/195110
- Clarence L. Musgrave Papers, 1839/19371
- Clement Dixon Johnston Papers, 1939/1979, bulk 1942/196223
- Cline M. Koon, Compiler, Koon Family Records, 1966/19744
- College of Agriculture and Life Sciences (CALS) Collection, 1900/20014