- Sally Jane Brown, Artist, Collection4
- Samuel Vaughan Wilson Papers1
- Sanjay Suchak photographs1
- School of Business records3
- Senator John D. (Jay) Rockefeller IV papers2
- Sexual Orientation, Gender Identity and Expression (SOGIE) Programming Records1
- Side by Side records8
- Sierra Club, West Virginia Chapter, Records1
- Sigma Sigma Sigma Collection2
- Society of Architectural Historians Women in Architecture Affiliate Group Records, 2020 -10
- Sold Property Files of the Virginia Dept. of General Services,1
- Sons of the American Revolution Virginia Society Williamsburg Chapter records3
- St. Mary's Hospital School of Nursing (Clarksburg, WV) Records1
- State and Local Government Policy Clinic records12
- Stewart Plein, Librarian and Collector, Papers2