- Alexandria Library Board Records (MS416), 1937/20208
- Alice Cartledge Cornett, Journalist, Papers, 1945/2017, bulk 1973/19921
- Alleghany Chapter, National Society of the Daughters of the American Revolution Records, 1890/20223
- Alpha Kappa Alpha Sorority, Inc. (Nu Chi Chapter) Collection, 1981/20201
- Alpha Sigma Alpha Collection, 1933/20186
- American Association of University Women (AAUW) Records, Harrisonburg, Virginia Branch, 1929/202521
- American Rhododendron Society Records, 1927/20222
- American Shakespeare Center Collection, 1987, bulk 1987/19951
- American Society of Pediatric Nephrology records, 1955/20229
- Ami Hirata, Ceramicist, Papers, 1940/20191
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20113
- Anchored., 20171
- Ann Magnuson, Performance Artist, Papers, 1973/202410
- Anna P. Sokolina Architectural Collection, 1924/20195
- Anna Schein, Collector, Feedsack Textile Bag Collection, 1925/19651