- RMC Faculty, Staff, and Alumni Files, 1818/202430
- Rachel H. Thomas, Student, Memory Book Regarding Student Days at Marshall College, 1931/2011, bulk 1931/19391
- Raleigh General Hospital Nurses Alumnae Association Records, 1940/20211
- Ralph Cohen papers and "New Literary History" records, 1948/20169
- Ralph Cohen papers, 1940/20134
- Randall S. Hawthorne Papers, 1935/2014, bulk 1980/20004
- Randolph H. Lytton historical Virginia collection1
- Ravindra S. Khare papers, 1938/20173
- Ray A. Jackson papers, 1944/20112
- Raymond and Paula McNamara, Artists, Papers, 1964/20161
- Rebecca Wood Watkin Architectural Drawings, 1940/20113
- Records and briefs of the Virginia Supreme Court, 1850/20161
- Records of HokiePRIDE, 1971/2015, bulk 1995/201315
- Records of Virginia Tech National Capital Region, 1991/201416
- Records of the 4-H All Stars, Virginia Chapter, 1964/20146