- E. Louise Righman, Genealogist, Research Materials, 1990/20221
- E. Maria Roth Architectural Collection, 1940/20103
- Earl Gregg Swem Library records, 1920/202413
- Earl W. Kennedy, Mine Inspector, Coal Company Mine Inspection Records, 1974/20131
- Earl and Jewell Ratliff Collection, 1860/2013, bulk 1920/19905
- East German poster collection political series1
- EcoTheater Papers and Maryat Lee Diaries, 1950/20091
- Edith R. White Papers, 1923/20107
- Education Collection, 20171
- Education and Outreach Photo Archives, 1950/201010
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/19001
- Effinger School Collection, 1909/201111
- Egon Verheyen papers, 1959/20084
- Eldon Bowman collection of Bowman family papers, 1797/20198
- Eleanor (Ellie) Schaul, Artist, Papers, 1950/20252