- Carol Barton papers, 1973/20201
- Congressman Nick Joe Rahall II Papers, 1970/20151
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20163
- Linwood H. Rose papers, 1949/2009, bulk 1985/20091
- Records of the Board of Visitors, 1908/20101
- Records of the Faculty, 1942/20141
- Records of the Office of Faculty Affairs, 1995/20161
- Records of the Virginia Tech Board of Visitors, 1873/20092
- Russell Stanger Papers, 1920/20081
- Senator John D. (Jay) Rockefeller IV papers, 1960/2015, bulk 1985/20141
- Southside Garden Club Records, 1914/20091
- Student Government Association records, 1915/20241
- University Communications and Marketing records, 1930/20171
- University Program Board records, 1972/20231