- M. Caldwell Butler Papers, 1945/20061
- M. Rosaria Piomelli Architectural Collection, 1960/19957
- M. Rupert Cutler Papers, 1930/2021, bulk 1962/202157
- M. Thomas Inge papers, 1879/20012
- Maddex Family Papers, 1937/20001
- Madison E. Marye Papers, 1932/20075
- Maggie Anderson, Poet, Papers, 1958/2017, bulk 1980/201280
- Major General Kenneth D. Gray Papers, 1990/20251
- Making of Virginia Architecture Collection, 1988/19942
- Malcolm Davis, Artist, Papers, 1970/201516
- Malcolm MacPherson Brownlee Civil War diary and transcription, 1862/20201
- Manuscripts Artifact Collection, 1800/201014
- Manuscripts Audiovisual Collection, 1920/201323
- Map of Montgomery County and Pulaski County with Blacksburg, Christiansburg and Radford, Virginia, 19951
- Marc Harshman, Poet Laureate of West Virginia, Papers, 1970/202393