- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19742
- Carolyn Rhodes Papers, 1924/201913
- Carter/Cash Family Collection, 1940/20092
- Cathryn Hankla papers, 1971/19926
- Charles Burchard Collection, 1935/198915
- Charles Lietwiler transportation collection, 1903/20053
- Charles M. Robinson and Principals Architectural Records, 1855/20121
- Charles Rodrigues playbill collection, 1879/200910
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/201814
- Charlotte Kaufman Papers, 1980/19901
- Christopher Bram Papers, 1968/2014, bulk 1975/20002
- Clan MacLeod Society USA Records, 1899/202262
- Claude Moore Health Sciences Library records, 1848/2019, bulk 1942/20252
- Clive L. DuVal papers2
- Clive L. DuVal papers, 1960/19942