- Dudley and Rexrode Family Papers, 1873/200510
- Edna Frederikson Papers, 1972/19922
- Edward M. Glick Papers, 1951/19881
- Eldon Bowman collection of Bowman family papers, 1797/201916
- Elizabeth "Libby" Custer Papers, 1930/19973
- Elmer Lewis Smith Papers, 1900/19811
- Emily Lewis Lee Papers, 1940/20069
- Emilyn Peterson Papers, 1929/2002, bulk 1929/19332
- Ernest M. Dickerman papers, 1904/200526
- Facilities Management Architectural Drawings, 1914/19831
- Faculty Senate Minutes, 1969/20075
- Fulks Run Ruritan Club records, 1958/20086
- Furious Flower Poetry Center Records, 1970/20244
- George Washington National Forest oral histories, 19943
- Gordon W. Miller Collection on Gabriel Thomas Barbee, 1787/20051