- Christopher A. Dorrance collection, 1750/20001
- Collection about Marion Montague Junkin, 1939/19791
- Collection of U. S. Army Infantry publications, 1967/2005, bulk 1967/19681
- Collection of research materials about William R. Clark, 1950/20081
- Cralle and Hurt Family Papers, 1801/20052
- Dale L. Walker Research Collection, 1914/19851
- Daniel T. Balfour Alumni Correspondence, 1974/19881
- Davidson Family Papers, 1870/19751
- Department of Athletics records4
- Diehl and Zink Family Papers, 1905/19801
- Douglas MacLeod Virginia Canal History Research Collection, 1950/20121
- E. D. Heppert Collection of research materials on Burning Spring/Ebbing Spring Church, 1972/19731
- East Lexington (Va.) Covered Bridge collection, 1934/19773
- Edward B. Hamer Correspondence, 1965/19731
- Effinger School Collection, 1909/20116