- Albert L. Sturm Papers, 1904/19884
- Alfred C. Payne Collection, 1917/20031
- Alice Langley Hsieh Papers,, 1943/19782
- Alleghany Chapter, National Society of the Daughters of the American Revolution Records,, 1890/20222
- Ann A. Hertzler Collection, 1863/2013, bulk 1974/20005
- Association for Women in Architecture Records, 1928/19923
- Barbara Woodward Architectural Collection, 1966/19922
- Beverly Willis Architectural Collection, 1954/19996
- Black, Kent, and Apperson Family Papers, 1779/19843
- Blacksburg Baptist Church Records, 1894/20079
- Carter/Cash Family Collection, 1940/20092
- Charles Burchard Collection, 1935/198923
- Diane Elliott Gayer Architectural Papers,, 1974/20231
- Dorothee Stelzer King Architectural Collection, 1950/20182
- Earl A. Thornton Papers, 1885/20002