- 275th Anniversary Celebration Records, 1967/1969, bulk 1967/19691
- A. H. Hand Papers, 1835/20092
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19668
- Adagio Press Collection, 1957/19935
- Adam Empie Papers, 1811/2004, bulk 1811/18503
- Adele Blow Chatfield-Taylor family papers, 1899/197722
- African American GI's Vietnam and West Germany Scrapbook, 1960/19691
- Albert E. Garrett, Jr. scrapbook, 1927/19741
- Albert E. Haak Scrapbook, 1947/19772
- Alfred R. Armstrong Papers, 1928/19761
- Alice Scantlebury Keener Papers, 1967/19702
- Alumni Association Photograph Collection, 1960/2010, bulk 1970/19902
- Alumni Association Records, 1833/2014, bulk 1950/200595
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/196022
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/197923