- Alan Clarke Railroad Research Papers, 1861/201217
- Alexander Mahood, Architect, Drawings for West Virginia University Building Projects, 1955/197931
- Ben Freedman, Artist and Professor, Papers and Artwork, 1960/20002
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/20183
- Cline M. Koon, Compiler, Koon Family Records, 1966/19741
- David Weimer, Collector, Seneca and Houze Glass Records, 1900/20054
- Davis Coal and Coke, Coal Mining and Railroad Company, Records, 1890/19807
- Don Knotts, Actor, Scripts, Sound Recordings, and Other Material, 1946/2006, bulk 1966/20001
- Dr. William A. Neal Papers, 1880/20162
- Emory L. Kemp Papers regarding Industrial History, 1735/202110
- Ethel Fike Friend, Teacher, Papers, 1884/1993, bulk 1937/19937
- Ewell Snuffer, Mine Foreman and Inspector, Diaries, 1955/19971
- Faris, Faris, and Stephens, Architects, Records, 1890/201343
- Festus P. Summers (1895-1971), Historian, Personal Diaries, 1953/19711
- Forbes, Anderson, and Hildebrand Families, Correspondence and Other Material, 1862/20132