- A. H. Hand Papers, 1835/20091
- A. L. McLeod Papers, 1964/19661
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661,019
- Adagio Press Collection, 1957/19933
- Adam Empie Papers, 1811/2004, bulk 1811/18502
- Adele Blow Chatfield-Taylor family papers, 1899/197717
- Albert E. Haak Scrapbook, 1947/19771
- Alumni Association Records, 1833/2014, bulk 1950/200569
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/196023
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/197932
- American Studies Program Records, 1960/20061
- Amos Koontz Papers II, 1865/197013
- Ann Buckles Papers, 1950/200873
- Ann Little Papers, 1947/19671
- Anne H. Cutler Papers, 1930/2013, bulk 1954/200022