- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/196911
- Records of the Virginia Tech Board of Visitors, 1873/20098
- Records of the Virginia Cooperative Extension, 1862/19976
- Student Government Association records, 1915/20245
- Ruth and Lowell Toliver Collection of Newman Family Papers, 1875/20053
- Southside Garden Club Records, 1914/20093
- University Communications and Marketing records, 1930/20173
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20162
- Ernest M. Dickerman papers, 1904/20052
- George Conoly Phillips Papers, 1909/20102
- Records of the Board of Visitors, 1908/20102
- Records of the Virginia Tech University Libraries, 1925/20062
- Robert James Sullivan Jr. papers, 1920/20132
- Albert Moore Reese, Zoology Professor, Miscellaneous Items, 1900/19701
- Allan Blank Papers, 1958/20091