- Blacksburg Baptist Church Records, 1894/20078
- Blow Family Papers, 1613/1960, bulk 1770/18752
- Board of Visitors Records, 1920/20104
- Board of Visitors records, 1757/20231
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Bruton Parish Church (Williamsburg, Va.) records, 1662/2010, bulk 1900/20002
- Calder Smith Sherwood, III Papers, 1899/197610
- Calvert Walke Tazewell Papers, 1900/19973
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19743
- Carl E. "Chick" Larsen papers, 1950/1989, bulk 1960/19801
- Carl Van Vechten - Mark Lutz Collection, 1881/19806
- Carolyn Rhodes Papers, 1924/20191
- Carter/Cash Family Collection, 1940/20092
- Cazenove Family Papers (MS212), 1786/19701
- Charles Burchard Collection, 1935/198919