- A. S. Lara papers, 1856/18611
- Alumni Association Records, 1924/201615
- American Association of University Professors (AAUP). James Madison University Chapter records, 1944/19886
- American Association of University Women (AAUW) Records, Harrisonburg, Virginia Branch, 1929/20252
- Anthony-Seeger Campus School Records, 1956/19822
- Betty Brown Clemmer and Willis Clemmer papers, 1920/2015, bulk 1943/19491
- Betty Clougherty Miller papers, 1945/20001
- Betty Coe Cinquegrana papers, 1960/20143
- Blackley Family papers, 1830/202092
- Bowman Family Papers, 1765/19981
- Charles Grattan Price Jr. and Don W. Thomas collection on the Chesapeake Western Railway, 1872/199619
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19563
- Charles T. Smith photographs, 1880/2007, bulk 1990/19995
- Chesapeake Western Railway Company Records, 1916/198222
- Christine Hoepfner Collection on the Shenandoah National Park, 1911/20002