- Thomas L. Williams collection, 1940/19901,856
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661,230
- Siler Family Papers, 1848/19681,145
- O.W. Riegel Papers, 1900/19921,093
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025691
- United Mine Workers of America, Health and Retirement Funds, Records, 1915/1989674
- Director's Correspondence (RG-01), 1927/2009672
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974571
- West Virginia University, President's Office, Records, 1864/1989503
- Francis J. McNamara papers, 1928/1997460
- Gregory A. Prince Mormon Studies Collection, 1813/2020438
- Harley Martin Kilgore (1893-1956), Senator, Papers, 1927/1956359
- American Public Transportation Association records, 1898/1999350
- John T. Parsons Papers, 1910/2000337
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/1974324