- Broadway souvenir theatre programs collection, 1942/19977
- C-SPAN records, 1809/2012, bulk 1978/20122
- C. Harrison Mann, Jr. map collection, 1579/19611
- C. Harrison Mann, Jr. papers, 1832/197924
- Carol D. Litchfield microbiology collection2
- Carol R. Lubin papers, 1960/19811
- Charles Baptie photograph collection70
- Charles Lietwiler transportation collection, 1903/20055
- Charles Rodrigues playbill collection, 1879/200915
- Civic Association of Hollin Hills records, 1940/201333
- Clarence A. Steele papers1
- Clarence J. Robinson papers, 1897/19781
- Clark E. Warburton papers, 1920/19794
- College of Visual and Performing Arts records, 1930/20154
- Cookbooks and cooking pamphlets collection, 1910/20081