- Blacksburg Music Club Records, 1907/197116
- Blacksburg Woman's Club Records, 1907/197220
- Blacksburg [Virginia] Odd Fellows Records, 1902/19698
- Blake W. Corson, Jr., Papers, 1861/1984, bulk 1934/197956
- Blue Ridge Springs Correspondence, 1895/19422
- Bobbitt Family Papers, 1825/19511
- British World War II Scrapbook, 1942/19442
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Buckhorn Coal Company Records, 1880/19615
- Byron Nelson Cooper Papers, 1925/19718
- C. Ernest Cooke Papers, 1920/19601
- C. Eugene Rowe Papers, 1949/19871
- Cadet Uniform Hardware and Insignia, 1877/19521
- Carl George Krieger Papers, 1930/19681
- Carneal and Johnston Architectural Drawings, 1939/19681