- William Faulkner Collection, 1824/2006102
- Richard Wright collection, 1806/2017101
- Blair family papers, 1821/1949100
- Richard Lee Morton papers, 1756/2006, bulk 1930/1969100
- Galt Papers (III), 1750/199198
- Margaret Freeman Cabell papers, 1910/198296
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/201187
- Nat T. Frame (1877-1948) Papers, 1914/194887
- International Association for Identification Records, 1842/2012, bulk 1910/195984
- Storer College Correspondence, Business Papers and Other Material, 1854/196484
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/195482
- James Hoge Ricks papers, 1916/195680
- Sheet Music Collection, 1827/197480
- American Lung Association of Virginia (ALAV) collection, 1907/200475
- Office of the President. John Stewart Bryan Records, 1933/194275