- Adalbert J. Volck Collection of Etchings, 1861/19791
- Adele Goodman Clark papers, 1849/19781
- Albert J. Wasserman Papers, 1925/20031
- Annie Laurie Miffleton Linton papers, 1922/19781
- Astoria Beneficial Club and Richmond Beneficial Insurance records, 1906/19471
- Ballard Hartwell Cabell collection, 1915/19691
- Billy DeBeck collection, 1915/19941
- Bryant Mangum American literature collection, 1920/20221
- Calvin T. Lucy Papers, 1914/19781
- Carl F. Emswiller, Jr. papers, 1922/20091
- Charles Henry Sykes cartoon collection, 1930/19421
- Children's Hospital of Richmond at VCU photographs and publications, 1911/19581
- Dr. Joseph J. Anderson papers, 1892/19801
- Dr. Lewis Hinton Bosher, Jr. papers, 1891/19941
- Dr. Rufus Livius Raiford papers, 1891/19631