- R. C. Nichols Scrapbook, 1925/19342
- R. Doyne Halbritter, Collector, Preston County Material, 1761/19371
- R. E. Lee Memorial Church Collection, 1869/19301
- R. Emmett Mockler Papers, 1900/19591
- R. Leonard Thompson Miscellaneous Postcards, 1907/19451
- R.E. Lee Camp, No. 1, Confederate Veterans Papers (SC-21), 1885/19583
- RMC Faculty, Staff, and Alumni Files, 1818/202410
- Racial and Ethnic Ephemera Collection, 1778/200515
- Radford, Virginia, East and West Wards, 19301
- Railroad Timetables, 1880/1968, bulk 1915/19271
- Railway mortgage certificates, 1880/19371
- Raleigh County Military and Church Records, 1908/1959, bulk 1947/19591
- Raleigh County Photographs for Pictorial History, 1880/1968, bulk 1890/19601
- Raleigh and Mercer Counties Photographs, 1870/2000, bulk 1910/19601
- Ralph Chesse papers, 1935/19751