- Arthur E. Scott photograph collection, 1910/19768
- Association for Women in Architecture Records, 1928/19921
- Audio Visual Collection, 1928/20151
- Austin-Twyman Papers, 1765/19397
- Bailey-Law Collection, 1825/197110
- Bell, Kent, Cloyd, Withrow Family Collection, 1780/19981
- Benjamin A. Banks Papers, 1855/197413
- Benjamin L. Wigfall Artist Archives and Mary Carter Wigfall Personal Papers, 1880/20232
- Black, Kent, and Apperson Family Papers, 1779/19845
- Blacksburg Baptist Church Records, 1894/20073
- Blair family papers, 1821/19495
- Blow Family Papers, 1613/1960, bulk 1770/18753
- Board of Visitors Records, 1920/20101
- Bright Family Papers, 1876/19332
- Brown, Coalter, Tucker Papers (I), 1790/19292