- Siler Family Papers, 1848/19681,159
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025548
- Gregory A. Prince Mormon Studies Collection, 1813/2020379
- Edward L. Stone/Borderland Coal Company Papers
1895-1937376
- Papers of the Low Moor Iron Company
1873-1927360
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974302
- Emory L. Kemp Papers regarding Industrial History, 1735/2021189
- West Virginia University, President's Office, Departmental, and Other Records, 1864/1989, bulk 1867/1920188
- West Virginia and Regional Postcard Collection, 1900/1960, bulk 1900/1940179
- Bailey-Law Collection, 1825/1971172
- Aubrey E. Strode papers, 1861/1969167
- Galt Papers (III), 1750/1991161
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960157
- Carter Glass Papers, 1820/1946155
- Restoration Files for the Historic Structures Report, 1750/2005150