- Siler Family Papers, 1848/19681,100
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025550
- Gregory A. Prince Mormon Studies Collection, 1813/2020365
- West Virginia University, President's Office, Departmental, and Other Records, 1864/1989, bulk 1867/1920181
- West Virginia and Regional Postcard Collection, 1900/1960, bulk 1900/1940171
- Emory L. Kemp Papers regarding Industrial History, 1735/2021165
- Perkins & Perkins Law Firm Records, 1751/1920163
- Aubrey E. Strode papers, 1861/1969158
- Galt Papers (III), 1750/1991153
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974148
- Restoration Files for the Historic Structures Report, 1750/2005146
- G. Walter Mapp Papers, 1873/1941140
- duPont family papers, 1767/1982134
- James Edwin Green, Photographer, Glass Plate Negatives and Other Material, 1900/1925, bulk 1900/1918127
- James Madison University Historic Photographs, 1909/2000116