- Academic Departments - Record Group 91
- Ackerly Family Papers8
- Anne McClung Collection, 1844/19661
- Carter Newman Bealer Papers, 1905/1962, bulk 1930/19501
- Dickinson Family Financial Records Collection, 1900/19483
- Ellinor Porcher Gadsden Papers, 1839/19751
- Fortnightly Club Papers, 1900/20151
- J.W. Brown and Company Ledgers, 1902/19141
- LeRoy Hodges Papers, 1908/19423
- Papers of John A. Washington III, 1798/19401
- Rockbridge Historical Society files on Lexington Fire Department, 1797/19291
- Town Council Minutes and Ordinance Books for the City of Lexington, Virginia, 1835/19582
- duPont family papers, 1897/19502