- Albert L. Sturm Papers, 1904/19881
- Ann A. Hertzler Collection, 1863/2013, bulk 1974/20001
- Anne Price Yates Papers II, 1898/20051
- Antoine Gaujot and Julien E. Gaujot Papers, 1840/19991
- Arthur B. Massey Papers, 1902/19611
- Arthur M. Squires Papers, 1888/1987, bulk 1940/19871
- Beattie Family University Memorabilia, 1875/19591
- Beulah O. Allen Collection,, 1905/1992, bulk 1920/19701
- Block Plan of the Virginia Polytechnic Institute, Blacksburg, Va., Showing the Proposed Layout of the Evans-Almirall Hot Water Heating Mains, 19091
- Carol M. Newman Papers, 1897/19581
- Clarence Paul Miles Papers, 1902/19601
- Claudius Lee Papers, 1887/19541
- College of Agriculture and Life Sciences (CALS) Collection,, 1900/20011
- Dayton M. Kohler Papers, 1889/19711
- Diploma Collection, 1877/19641