- Siler Family Papers, 1848/19681,165
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025449
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974399
- Gregory A. Prince Mormon Studies Collection, 1813/2020314
- Papers of the Low Moor Iron Company
1873-1927301
- Henry Gassaway Davis (1823-1916) Papers, 1799/1919211
- Galt Papers (III), 1750/1991186
- Emory L. Kemp Papers regarding Industrial History, 1735/2021173
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960149
- Restoration Files for the Historic Structures Report, 1750/2005143
- West Virginia University, President's Office, Departmental, and Other Records, 1864/1989, bulk 1867/1920137
- Records of the Office of the President, John McLaren McBryde, 1900/1907126
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900114
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954114
- Blair family papers, 1821/1949111