- Siler Family Papers, 1848/19681,102
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025449
- Gregory A. Prince Mormon Studies Collection, 1813/2020298
- Henry Gassaway Davis (1823-1916) Papers, 1799/1919196
- Galt Papers (III), 1750/1991177
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974154
- Emory L. Kemp Papers regarding Industrial History, 1735/2021152
- West Virginia University, President's Office, Departmental, and Other Records, 1864/1989, bulk 1867/1920143
- Restoration Files for the Historic Structures Report, 1750/2005139
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960113
- James I. Robertson Jr. Papers, 1849/201194
- Blair family papers, 1821/194984
- West Virginia University, Women's Studies Center, Women's Centenary, Records, 1849/2000, bulk 1980/199279
- Duke family law firm papers, 1820/195974
- Inge Horton Architectural Collection, 1964/199974