- Siler Family Papers, 1848/19681,158
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974360
- Gregory A. Prince Mormon Studies Collection, 1813/2020298
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025262
- Papers of the Low Moor Iron Company
1873-1927241
- Henry Gassaway Davis (1823-1916) Papers, 1799/1919223
- Emory L. Kemp Papers regarding Industrial History, 1735/2021170
- Galt Papers (III), 1750/1991170
- J. Hoge Tyler Family Collection, 1802/1956154
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960152
- Restoration Files for the Historic Structures Report, 1750/2005141
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/1865121
- West Virginia University, President's Office, Departmental, and Other Records, 1864/1989, bulk 1867/1920114
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954113
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900109