- Anna Burton Ellett Collection, 1751/19321
- Association for the Preservation of Virginia Antiquities, Montgomery County Branch Papers, 1754/1996, bulk 1958/19831
- Attorney's Suit and Collection Record, 1896/19291
- Bank of Blacksburg Minute Book, 1892/19031
- Black, Kent, and Apperson Family Papers, 1779/19841
- Blacksburg Baptist Church Records, 1894/20071
- Blacksburg [Virginia] Presbyterian Church Land Deeds, 1850/19241
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Croy Family Papers, 1859/19381
- Dorothy H. Bodell Papers, 1850/19961
- George W. L. Kabrich Family Papers, 1850/1947, bulk 1850/19041
- Harvey Lee Price Papers, 1853/19491
- Henry H. Hill Collection, 1893/19631
- Historical Maps Collection, 1500/20231
- Independent Order of St. Luke Records, 1877/19701