- Acker Family Diaries, 1880/19061
- Barnhart Family Papers, 1836/19441
- Bowman Family Papers, 1765/19981
- Charles T. Smith photographs, 1880/2007, bulk 1990/19991
- Elizabeth A. Wenger Papers, 1884/19511
- Harrisonburg-Rockingham Historical Society Collection, 1740/19501
- Heatwole Family Papers, 1838/20011
- Hedrick Family Papers, 1856/19591
- Henkel Family Papers, 1801/20081
- J. W. Tate Ledgers, 1888/19051
- John G. Stewart Papers, 1761/2002, bulk 1953/19731
- John L. Heatwole Collection of Shenandoah Valley History, 1802/19011
- Liskey Collection of Heavner Family Papers, 1788/19671
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19101
- McHone Brothers (LLC) Collection of Houck Tannery Records, 1870/19131