- James Elliott Walmsley Collection, 1810/19391
- Jean Carruthers Boatwright Correspondence, 1885/19481
- John Atkinson Cunningham Photograph Collection, 1890/18911
- Katherine Courtenay Johnston Collection, 1829/19461
- Lucy Irvine Collection, 18912
- Mary Louise Gayle Bland Collection, 1891/18941
- Mattoon Family Collection, 1870/19661
- Paulett Family Business Records, 1877/19294
- Pi Gamma Mu Collection, 1818/19702
- Planters Bank President Portraits, 1870/19051
- Registrar's Office Ledgers, 1884-1994, 1884/19945
- Richard Couture Papers, 1860/20031
- Rose Womack Correspondence, 1891/18934
- Rosemary Sprague Collection, 1862/19911
- Ruffner Family Association Collection, 1811/2014, bulk 1999/20144