- African American man tintype portrait, 1865/19001
- Albert Frederick Wilson papers, 1840/19341
- Albert Taylor Bledsoe and Sophia Bledsoe Herrick letters, 1858/19081
- Alderman family papers, 1779/19611
- Alfred Oscar Elzner sketch book and album, 1883/19231
- Alfred Tennyson papers, 1875/18761
- Anna Maria Hickman Otis Mead Chalmers family papers, 1821/18971
- Arlene Keeling Collection, 1861/20061
- Armstead L. Robinson papers, 1848/2001, bulk 1967/19921
- Arthur J. Morris memorabilia, 1884/19921
- Attorney's ledger, 1884/18901
- Aubrey E. Strode papers, 1861/19691
- Barbara Brodie Nursing History Collection Additions, 1890/19891
- Barrett Minor Literary collection, 1802/19441
- Benjamin F. Buchanan memorabilia, 1861/19831