- Business Office Accounting Ledgers, 1884/19236
- Dabney Lancaster and Lancaster Family Records, 1848/19745
- Ruffner Family Association Collection, 1811/2014, bulk 1999/20145
- Bugg Family Collection., 1876/19574
- Registrar's Office Ledgers, 1884-1994, 1884/19944
- Anne Atkinson Chamberlayne Collection., 1742/19633
- Commencement Programs Collection, 1863/20213
- Harwood Family Collection, 1806/19833
- Katherine Courtenay Johnston Collection, 1829/19463
- Paulett Family Business Records, 1877/19293
- Dr. Wayne McWee Historical Newspapers, 1863/19622
- Faculty Meeting Minutes, 1884/19642
- James Elliott Walmsley Collection, 1810/19392
- Kate Childress Autograph Book, 1884/18892
- Pi Gamma Mu Collection, 1818/19702