- David Hunter Strother, Artist, Artwork and Papers, 1744/1996, bulk 1833/188750
- Duke family law firm papers, 1820/195950
- Richard Wright collection, 1806/201750
- Snyder Family papers, 1850/190149
- Thomas Browse Family Papers, 1785/1942, bulk 1830/191049
- Ohio County (W. Va.) Court Records and Miscellaneous Papers, 1772/1954, bulk 1777/193047
- Peter family papers, 1722/193246
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/199543
- Oren F. Morton (1857-1926) Papers, 1799/192643
- Randolph Huntington papers, 1860/190843
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/190042
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/201141
- Cynthia Beverley Tucker Washington Coleman Papers, 1834/192841
- Morton-Halsey family papers, 1833/195141
- Bell, Kent, Cloyd, Withrow Family Collection, 1780/199840