- Adolphus DeBussey, Soldier, Civil War Letters, 1861/1998, bulk 1861/18711
- Alan Clarke Railroad Research Papers, 1861/20124
- Albert Blakeslee White (1856-1941) Papers, 1888/19291
- Allen Family Papers, 1766/19337
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20112
- Appalachian Prints Collection, 1839/2010, bulk 1859/19098
- Archibald W. Campbell (1839-1899), Newspaperman, Papers, 1855/1941, bulk 1855/18992
- Arthur I. Boreman (1823-1896) Papers, 1861/18952
- Arthur I. Boreman Papers, 1830/19496
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/190016
- Barbara Howe, History Professor, Research Papers regarding the History of the College of Arts and Sciences, 1870/2005, bulk 1990/20052
- Braxton County (W. Va.) Court Records and Miscellaneous Papers, 1830/19532
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/19183
- Capt. William Sommerville (1756-1826) Papers, 1799/18882
- Charles L. Robinson, Collector, Papers of a Marion County Family, 1872/19272