- Historical Photograph Collection, 1850/2010202
- Restoration Files for the Historic Structures Report, 1750/2005122
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/187586
- Robert Waldsmith Collection of stereographs and cabinet cards, 1856/198156
- Peter family papers, 1722/193244
- Papers of the Mount Vernon Ladies' Association, 1858/201640
- Geo. Gregory Smart collection of Washington and Mount Vernon ephemera, 1793/201728
- Papers of the Superintendent and Resident Director, 1850/199628
- Lily Laughton Papers, 1850/189122
- Financial Records of the Mount Vernon Ladies' Association, 1858/201517
- Publications and Printed Material of the Mount Vernon Ladies' Association, 1854/201610
- Superintendent's Letter Books, Diaries, and Monthly Reports - collection of bound volumes, 1885/196710
- Harrison H. Dodge Papers, 1816/19369
- Historic newspapers collection, 1757/19579
- Morley Jeffers Williams Collection, 1602/19678